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Age-based comparability of TAVR outcomes in Vietnamese sufferers with aortic stenosis

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Age-based comparability of TAVR outcomes in Vietnamese sufferers with aortic stenosis

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Saying a brand new article publication for Cardiovascular Improvements and Purposes journal. The rising variety of aged sufferers with extreme aortic valve stenosis present process transcatheter aortic valve alternative (TAVR) has prompted issues relating to their medical outcomes in contrast with the youthful inhabitants. This research evaluated the outcomes of TAVR on the idea of age group (<80 or ≥80 years) amongst Vietnamese sufferers with extreme aortic valve stenosis at intermediate surgical threat.

From March 2017 to December 2022, 21 sufferers ≥80 years of age and 69 sufferers <80 years of age underwent TAVI at a single middle. Scientific traits, procedures, and outcomes at 30 days and 1 yr have been in contrast with the Valve Educational Analysis Consortium (VARC-2) standards.

Sufferers ≥80 years of age had a better prevalence of comorbidities however no vital variations in different medical traits and procedures. No statistically vital variations have been noticed in procedural mortality (4.8% vs. 0.0%, P = 0.233), 30-day mortality (5.0% vs. 1.5%, P = 0.405), and 1-year mortality (11.8% vs. 3.7%, P = 0.241) between age teams. Main endpoints at specified time factors additionally confirmed no vital variations.

TAVR in sufferers with aortic stenosis at intermediate surgical threat has related medical outcomes at 30 days and 1 yr, in accordance with VARC-2 standards, with no statistically vital age-associated variations (≥80 vs. <80 years). Nonetheless, additional research with bigger affected person populations are wanted to raised perceive the consequences of age on TAVI outcomes in sufferers with related traits.

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Journal reference:

Nguyen, Okay. Q., et al. (2024) Transcatheter Aortic Valve Substitute in Sufferers ≥80 and <80 Years of Age with Aortic Valve Stenosis at Reasonable Surgical Threat: Findings from an Observational Examine within the Vietnamese Inhabitants. Cardiovascular Improvements and Purposes. doi.org/10.15212/CVIA.2024.0003.

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