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Final Up to date January 2022
This can be a present listing of each research we’ve discovered on the security and efficacy of hydroxyapatite toothpaste. We created this to be a useful resource for the purposeful dentist neighborhood, so be at liberty to bookmark it, share it extensively together with your sufferers, and electronic mail us you probably have a research so as to add.
I have to give credit score to Jacqueline Carcaramo, RDH (@the.flossophy on Instagram) who impressed this concept. After we each realized we have been conserving our personal repository of research on this matter, we realized we might be a part of forces and publish this database for the advantage of purposeful dentists and hygienists in all places.
Research on Hydroxyapatite Toothpaste Efficacy & Security
Biomimetic hydroxyapatite and caries prevention: a scientific evaluate and meta-analysis
Based mostly on this systematic evaluate and meta-analysis, it may be concluded that biomimetic hydroxyapatite-containing, fluoride-free oral care merchandise are efficient in decreasing dental decay, particularly in youngsters.
Conclusion: There’s good proof that hydroxyapatite in oral care merchandise within the absence of fluoride successfully reduces caries.
This research goals to critically summarize the literature about nano-hydroxyapatite, particularly the advantages of utilizing nano-hydroxyapatite for its preventive, restorative, and regenerative functions in dentistry.
Demineralized dentin infiltrated with silica NPs seems to encourage heterogeneous mineralization of the dentin collagen matrix following publicity to a synthetic saliva resolution.
Reconsidering remineralization methods to incorporate nanoparticle hydroxyapatite.
This in-vitro research documented the deposition of nanoparticle hydroxyapatite on demineralized enamel surfaces after therapy with an experimental remineralization gel. This discovering helps consideration of a further strategy to remineralization that features pH neutralization methods and nanoparticle hydroxyapatite crystals.
Impact of nano-hydroxyapatite focus on remineralization of preliminary enamel lesion in vitro
The aim of the analysis was to find out the impact of nano-hydroxyapatite concentrations on preliminary enamel lesions beneath dynamic pH-cycling situations.
Remineralization Potential of Nano-Hydroxyapatite on Preliminary Enamel Lesions: An in vitro Examine
The remineralization impact of nano-HA on demineralized bovine enamel is investigated beneath pH biking situations via floor and cross-sectional microhardness (CSMH) checks and polarized gentle microscopy (PLM). The share of floor microhardness restoration and built-in mineral loss obtained from CSMH checks demonstrated that nano-HA supplies higher remineralization than micro-HA.
Combined Results of Nano-Hydroxyapatite and NaF on Remineralization of Early Caries Lesion
The goal of this research was to judge the mixed results of a nano-HA and fluoride mouthrinse on an early caries lesion in human enamel utilizing an in vitro cycle remineralization and therapy mannequin.
Effectiveness of nano-hydroxyapatite toothpaste in decreasing dentin hypersensitivity: a double-blind randomized managed trial
A double-blind randomized scientific trial that in contrast the efficacy in decreasing dentin hypersensitivity of a dentifrice formulation containing nano-hydroxyapatite with a fluoride dentifrice and a placebo.
Nano-HA and NAF mouthrinses can significantly improve remineralization and enhance tooth microhardness.
Remineralization Potential of New Toothpaste Containing Nano-Hydroxyapatite
The outcomes confirmed that there have been no important variations in Vickers Hardness Quantity values between the 2 toothpastes (P>0.05). A toothpaste containing nano-sized hydroxyapatite has the potential to remineralize an incipient caries lesion. As well as, the addition of fluoride had no synergistic impact on remineralization.
The research was carried out in vitro and in vivo, evaluating the hydroxyapatite toothpaste with two others toothpaste containing completely different fluorine concentrations. The coating impact of the micro-structured Hydroxyapatite nanoparticles reintegrates the enamel with a biomimetic movie reproducing the construction and the morphology of the biologic Hydroxyapatite of the enamel. As demonstrated, the coating is because of the deposit of a brand new layer of apatite, which presents fewer particles than the pure enamel, not primarily based on the chemical—bodily adjustments occurring in fluorinated toothpastes. Furthermore, it reveals resistance to brushing as a consequence of chemical bonds between the artificial and pure crystals of the enamel.
Comparison of hydroxyapatite and fluoride oral care gels for remineralization of preliminary caries: a pH-cycling research
Hydroxyapatite-based gel (15% HAP) was as efficient as fluoride-based gel (12,500 ppm F−) in remineralizing preliminary caries lesion.
Enamel and dentine remineralization by nano-hydroxyapatite toothpastes
Toothpastes containing n-HAp revealed increased remineralizing results in comparison with amine fluoride toothpastes with bovine dentine, and comparable tendencies have been obtained for enamel.
Remineralization of early caries by a nano-hydroxyapatite dentifrice
The aim of this randomized, double-blind, crossover, in situ research was to judge the efficacy of nano-hydroxyapatite (nHAP) dentifrices on caries remineralization and demineralization inhibition. nHAP dentifrice prompted remineralization similar to a fluoride dentifrice, and inhibited caries improvement, thus suggesting that an nHAP dentifrice might be an efficient different to fluoride toothpaste.
Artificial Biomimetic Carbonate-Hydroxyapatite Nanocrystals for Enamel Remineralization
The experimental outcomes level out the chance to make use of supplies different to fluoride compounds which is often utilized to distinction the mechanical abrasions and acid assaults. The apatitic artificial coating is much less crystalline than enamel pure apatite, however consists of a brand new biomimetic apatitic mineral deposition which progressively fills the floor scratches. Due to this fact the applying of biomimetic CHA could also be thought of an progressive strategy to distinction the acid and micro organism assaults.
- HApNPs allowed Ca2+ and PO43− launch in low pHs.
- HApNPs allow remineralization of caries-like enamel lesions.
This research investigated the flexibility of hydroxyapatite nanoparticles (nano-HA) to remineralize enamel, and their impact on sealant microleakage and shear bond energy (SBS).
The put up Present Analysis on Hydroxyapatite Toothpaste Efficacy and Security appeared first on Ask the Dentist.
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